Pictured: Lobby card from Nikki, Wild Dog of the North, probably the best Malamute movie ever made, from author's collection. Copyright Walt Disney Pictures, 1961.
Antarctica a.k.a. Nankyoku monogatari (1983)
Eight Below (2006)
Indiana Jones and the Last Crusade (1989)
Iron Will (1994)
Kayla a.k.a. Kayla: A Cry in the Wilderness (1999)
The Lost Boys (1987)
Nikki, Wild Dog of the North a.k.a. Nomads of the North (1961)
On Deadly Ground (1994)
The Thing From Another World (1951)
White Fang 2: Myth of the While Wolf (1994)
Also, a famous Malamute mix was Jed, star of The Thing (1982), The Journey of Natty Gann (1985), and White Fang (1991).
Malamutes of TV include the ones from Dr. Quinn, Medicine Woman (1993), White Fang (1993), and The Call of the Wild (2000).